Bookmark Us
All Food, Diet and Health News 
 Misc. News
 Must-Read News
 Letter to Editor
 Featured Products
 Recalls & Alerts
 Consumer Affair
 Non-food Things
 Health Tips
 Interesting Sites
 Diet & Health
 Heart & Blood
 Body Weight
 Children & Women
 General Health
 Food & Health
 Food Chemicals
 Biological Agents
 Cooking & Packing
 Agri. & Environ.
 Laws & Politics
 General Health
 Drug News
 Mental Health
 Infectious Disease
 Other News
 Food Consumer
 FC News & Others

Search Foodconsumer & Others

Add to Google
Add to My Yahoo
Newsfeed news feed
Su bmit news[release]

More than 100 credit cards available at from, you can pick more than 100 credit cards

Diet & Health : Children & Women Last Updated: Apr 20, 2011 - 9:38:09 AM

Pregnant women should avoid using statins
By David Liu Ph.D.
Dec 9, 2008 - 8:31:33 AM

E.mail t.his a.rticle
 P.rinter f.riendly p.age
Get n.ewsletter
Tuesday Dec 9, 2008 ( -- Women during pregnancy should avoid taking statins of any kind and using such drugs could lead to serious congenital anomalies in children of pregnant women, a study published in the Journal of Cellular and Molecular Medicine suggests.


Clinical guidelines currently recommend that pregnant women should avoid statins, but the advice is based on the assumption that cholesterol is essential for normal fetal development and clinicians do not know that using statins during pregnancy could do more harm than simply lowering cholesterol.


A 2007 study has already suggested that fat soluble or lipophilic statins may increase the risk of congenital anomalies in children of pregnant women.   But it is unknown whether water-soluble statins would have the same detrimental effects.


A new study led by researchers from the University of Manchester has now showed that water-soluble or hydrophilic statins like prevastatin can also affect placental development potentially resulting in worse pregnancy outcomes.


Obesity and type 2 diabetes patients are often given statins to lower circulating levels of cholesterol and reduce the risk of heart disease. The study suggests that pregnant women should not be given any type of statin.


Dr Melissa Westwood at the Maternal and Fetal Health Research Centre at St Mary's Hospital, Manchester said the actions of statins are not limited to the regulation of cholesterol levels and they can affect the production of other chemicals in the body as well.


"Our study examined the effects that both lipophilic and hydrophilic statins had on a key biological system that is crucial for maintaining the normal function of the placenta, which acts as the nutrient-waste exchange barrier between mother and fetus."


Dr. Westwood and colleagues tested two statins, one water soluble and the other fat soluble in a placental-tissue model.   And they found the fat -soluble statin, cerivastatin reduced growth of the placenta, which was expected.


Surprisingly, they also found that prevastatin, the water soluble stain which had been believed to be suitable for use in pregnancy, had the same detrimental effect.


"These results clearly show that the effect of statins on the placenta is not dependent on their lipophilicity as had previously been suggested," said Dr Westwood.


"While hydrophilic statins have not been reported to increase the incidence of fetal malformations, our research suggests that they will have a detrimental effect on placental growth, which is likely to result in poor pregnancy outcome.


The findings justify the recommendation that pregnant women should avoid the use of any type of statin once they plan to start a family or when a pregnancy is suspected or confirmed.

© 2004-2008 by unless otherwise specified

Top of Page


Search Consumer-friendly Health Sites

We have moved to Food Consumer . Org

disclaimer | advertising | jobs | privacy | about us | newsletter | Submit news/articles
link partners: | Buy Viagra | |
Buy a home | Auto Insurance | Mortgage refinancing | | Take Your Blog to a Higher Level
© Copyright 2004 - 2008 All rights reserved

Disclaimer: What's published on this website should be considered opinions of respective writers only and which has no political agenda nor commercial ambition may or may not endorse any opinion of any writer. No accuracy is guaranteed although writers are doing their best to provide accurate information only. The information on this website should not be construed as medical advice and should not be used to replace professional services provided by qualified or licensed health care workers. The site serves only as a platform for writers and readers to share knowledge, experience, and information from the scientific community, organizations, government agencies and individuals. encourages readers who have had medical conditions to consult with licensed health care providers - conventional and or alternative medical practitioners.