Environment
11th Report on Carcinogens
By National Toxicology Program
Apr 14, 2008 - 8:29:51 AM

11th Report on Carcinogens

http://ntp.niehs.nih.gov/go/ 16183

U.S. Department of Health and Human Services Public Health Service National Toxicology Program Pursuant to Section 301(b) (4) of the Public Health Service Act as Amended by Section 262, PL 95-622 Official Citation: Report on Carcinogens, Eleventh Edition; U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program . Table of Contents I. Introduction II. Carcinogens Listed in the Eleventh Report A. Known to be Human Carcinogens B. Reasonably Anticipated to be Human Carcinogens III. Substance Profiles Acetaldehyde 2-Acetylaminofluorene Acrylamide Acrylonitrile Adriamycin® (Doxorubicin Hydrochloride) Aflatoxins Alcoholic Beverage Consumption 2-Aminoanthraquinone o-Aminoazotoluene 4-Aminobiphenyl 1-Amino-2,4-dibromoanthraquinone 1-Amino-2-methylanthraquinone Amitrole o-Anisidine Hydrochloride Arsenic Compounds, Inorganic Asbestos Azacitidine Azathioprine Benzene Benzidine and Dyes Metabolized to Benzidine Benzidine Dyes Metabolized to Benzidine Benzotrichloride Beryllium and Beryllium Compounds Bromodichloromethane 2,2-bis(Bromomethyl)-1,3-propanediol (Technical Grade) 1,3-Butadiene 1,4-Butanediol Dimethylsulfonate (Myleran®) Butylated Hydroxyanisole (BHA) Cadmium and Cadmium Compounds Carbon Tetrachloride Ceramic Fibers (Respirable Size) Chlorambucil Chloramphenicol Chlorendic Acid Chlorinated Paraffins (C12, 60% Chlorine) 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea bis(Chloroethyl) Nitrosourea Chloroform bis(Chloromethyl) Ether and Technical-Grade Chloromethyl Methyl Ether 3-Chloro-2-methylpropene 4-Chloro- o-phenylenediamine Chloroprene p-Chloro- o-toluidine and p-Chloro- o-toluidine Hydrochloride Chlorozotocin Chromium Hexavalent Compounds C.I. Basic Red 9 Monohydrochloride Cisplatin Coal Tars and Coal Tar Pitches Cobalt Sulfate Coke Oven Emissions p-Cresidine Cupferron Cyclophosphamide Cyclosporin A Dacarbazine Danthron (1,8-Dihydroxyanthraquinone) 2,4-Diaminoanisole Sulfate 2,4-Diaminotoluene Diazoaminobenzene 1,2-Dibromo-3-chloropropane 1,2-Dibromoethane (Ethylene Dibromide) 2,3-Dibromo-1-propanol tris(2,3-Dibromopropyl) Phosphate 1,4-Dichlorobenzene 3,3´-Dichlorobenzidine and 3,3´-Dichlorobenzidine Dihydrochloride Dichlorodiphenyltrichloroethane (DDT) 1,2-Dichloroethane (Ethylene Dichloride) Dichloromethane (Methylene Chloride) 1,3-Dichloropropene (Technical Grade) Diepoxybutane Diesel Exhaust Particulates Diethyl Sulfate Diethylstilbestrol Diglycidyl Resorcinol Ether 3,3´-Dimethoxybenzidine and Dyes Metabolized to 3,3´-Dimethoxybenzidine 3,3´-Dimethoxybenzidine Dyes Metabolized to 3,3´-Dimethoxybenzidine 4-Dimethylaminoazobenzene 3,3´-Dimethylbenzidine and Dyes Metabolized to 3,3´-Dimethylbenzidine 3,3´-Dimethylbenzidine Dyes Metabolized to 3,3´-Dimethylbenzidine Dimethylcarbamoyl Chloride 1,1-Dimethylhydrazine Dimethyl Sulfate Dimethylvinyl Chloride 1,4-Dioxane Disperse Blue 1 Epichlorohydrin Erionite Estrogens, Steroidal Ethylene Oxide Ethylene Thiourea di(2-Ethylhexyl) Phthalate Ethyl Methanesulfonate Formaldehyde (Gas) Furan Glass Wool (Respirable Size) Glycidol Hepatitis B Hepatitis C Heterocyclic Amines 2-Amino-3,4-dimethylimidazo[4,5- f]quinoline (MEIQ) 2-Amino-3,8-dimethylimidazo[4,5- f]quinoxaline (MEIQx) 2-Amino-3-methylimidazo[4,5- f]quinoline (IQ) 2-Amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) Hexachlorobenzene Hexachloroethane Hexamethylphosphoramide Human Papillomaviruses: Some Genital-Mucosal Types Hydrazine and Hydrazine Sulfate Hydrazobenzene Ionizing Radiation X-Radiation and Gamma Radiation Neutrons Radon Thorium Dioxide Iron Dextran Complex Isoprene Kepone® (Chlordecone) Lead and Lead Compounds Lindane and Other Hexachlorocyclohexane Isomers Melphalan Methoxsalen with Ultraviolet A Therapy (PUVA) 2-Methylaziridine (Propylenimine) 4,4´-Methylenebis(2-chloroaniline) 4,4´-Methylenebis( N,N-dimethyl)benzenamine 4,4´-Methylenedianiline and its Dihydrochloride Salt Methyleugenol Methyl Methanesulfonate N-Methyl- N´-nitro- N-nitrosoguanidine Metronidazole Michler's Ketone (4,4'-(Dimethylamino)benzophenone) Mineral Oils (Untreated and Mildly Treated) Mirex Mustard Gas Naphthalene 2-Naphthylamine Nickel Compounds and Metallic Nickel Nickel Compounds Metallic Nickel Nitrilotriacetic Acid o-Nitroanisole Nitroarenes (selected) 1,6-Dinitropyrene 1,8-Dinitropyrene 6-Nitrochrysene 1-Nitropyrene 4-Nitropyrene Nitrobenzene Nitrofen (2,4-Dichlorophenyl- p-nitrophenyl Ether) Nitrogen Mustard Hydrochloride Nitromethane 2-Nitropropane N-Nitrosodi- n-butylamine N-Nitrosodiethanolamine N-Nitrosodiethylamine N-Nitrosodimethylamine N-Nitrosodi- n-propylamine N-Nitroso- N-ethylurea 4-( N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone N-Nitroso- N-methylurea N-Nitrosomethylvinylamine N-Nitrosomorpholine N-Nitrosonornicotine N-Nitrosopiperidine N-Nitrosopyrrolidine N-Nitrososarcosine Norethisterone Ochratoxin A 4,4´-Oxydianiline Oxymetholone Phenacetin and Analgesic Mixtures Containing Phenacetin Phenacetin Analgesic Mixtures Containing Phenacetin Phenazopyridine Hydrochloride Phenolphthalein Phenoxybenzamine Hydrochloride Phenytoin Polybrominated Biphenyls (PBBs) Polychlorinated Biphenyls (PCBs) Polycyclic Aromatic Hydrocarbons, 15 Listings Benz[ a]anthracene Benzo[ b]fluoranthene Benzo[ j]fluoranthene Benzo[ k]fluoranthene Benzo[ a]pyrene Dibenz[ a,h]acridine Dibenz[ a,j]acridine Dibenz[ a,h]anthracene 7 H-Dibenzo[ c,g]carbazole Dibenzo[ a,e]pyrene Dibenzo[ a,h]pyrene Dibenzo[ a,i]pyrene Dibenzo[ a,l]pyrene Indeno[1,2,3- cd]pyrene 5-Methylchrysene Procarbazine Hydrochloride Progesterone 1,3-Propane Sultone ß-Propiolactone Propylene Oxide Propylthiouracil Reserpine Safrole Selenium Sulfide Silica, Crystalline (Respirable Size) Soots Streptozotocin Strong Inorganic Acid Mists Containing Sulfuric Acid Styrene-7,8-oxide Sulfallate Tamoxifen 2,3,7,8-Tetrachlorodibenzo- p-dioxin (TCDD); "Dioxin" Tetrachloroethylene (Perchloroethylene) Tetrafluoroethylene Tetranitromethane Thioacetamide 4,4´-Thiodianiline Thiotepa Thiourea Tobacco Related Exposures Environmental Tobacco Smoke Smokeless Tobacco Tobacco Smoking Toluene Diisocyanate o-Toluidine and o-Toluidine Hydrochloride Toxaphene Trichloroethylene 2,4,6-Trichlorophenol 1,2,3-Trichloropropane Ultraviolet Radiation Related Exposures Solar Radiation Sunlamps or Sunbeds, Exposure to Broad-Spectrum Ultraviolet (UV) Radiation Ultraviolet A Radiation Ultraviolet B Radiation Ultraviolet C Radiation Urethane Vinyl Bromide Vinyl Chloride 4-Vinyl-1-cyclohexene Diepoxide Vinyl Fluoride Wood Dust IV. Tables Table 1.Chemicals Nominated to the NTP for In-Depth Toxicological Evaluation or Carcinogenesis Testing in Fiscal Years 1988-2001 Table 2.CDC/NIOSH Response to Inquiries about Carcinogens Listed in the Eleventh Report on Carcinogens V. Report on Carcinogens Nomination Review Procedures Appendices A. Manufacturing Processes, Occupations, and Exposure Circumstances Classified by IARC as Category 1, Carcinogenic to Humans B. Agents, Substances, Mixtures, or Exposure Circumstances Delisted from the Report on Carcinogens C. Agents, Substances, Mixtures, or Exposure Circumstances Reviewed but not Recommended for Listing in the Report on Carcinogens D. List of Participants E. Glossary F. Acronyms and Abbreviations G. Units of Measurement Indexes A. Names and Synonyms used in RoC Substance Profiles B. CAS Registry Numbers