Friday Nov. 2008 (foodconsumer.org) -- One study we have
recently reported found that statins lowered plasma C-reactive protein or CRP
in people with relatively high CRP, but normal cholesterol levels.
This suggests that taking statins in those who have
normal cholesterol, but high levels of CRP may reduce the risk of
Statins are intended for people to lower their
cholesterol levels so that they may reduce risk of heart disease.
But it has been known that CRP is another
risk factor for heart disease.
Because of this, it is apparently that taking statins may
help people with normal cholesterol but high CRP reduced cardiovascular risk.
The problem with statins is that the cost and side
Is there any alternative, which is equally effective, but
much safer than statins?
The answer is
One study published in Oct 2008 issue of Free Radical
Biology and Medicine suggests that taking as much as 1,000 mg of vitamin C per
day is equally effective.
The study led by Block G and colleagues of the University
of California in Berkley, California found that taking vitamin C reduced CRP by
25 percent in those with CRP indicative of elevated cardiovascular risk.
Block and colleagues wanted to know whether vitamin C or
E could reduce CRP, which as a biomarker of cardiovascular risk has something to
do with inflammation. Vitamin C and E as antioxidants are supposed to have an
effect on inflammation.
For the study, the researchers enlisted 396 health
nonsmokers and randomized them into three groups. One group of subjects were
assigned 1,000 mg per day of vitamin C, the second group 800 iU
per day of vitamin E and the third group a
placebo. The supplementation lasted for two months.
The overall mean CRP concentration was lower, 0.85 mg/L
and no treatment effect was observed when all participants were included in the
However, a significant 25
percent reduction by vitamin C was observed among those who had CRP indicative
of elevated cardiovascular risk.
This effect was similar to that achieved by statins, the
authors of the study said.
However, there is no significant effect observed with
Block and team also found CRP is generally high in obese
Over 75 percent of obese people
had CRP greater than 1.0 mg/L.
that research is needed to determine whether reducing CRP could reduce diseases
related to obesity.
Disclaimer: What's published on this website should be considered opinions of respective writers only and foodconsumer.org which has no political agenda nor commercial ambition may or may not endorse any opinion of any writer. No accuracy is guaranteed although writers are doing their best to provide accurate information only.
The information on this website should not be construed as medical advice and should not be used to replace professional services provided by qualified or licensed health care workers. The site serves only as a platform for writers and readers to share knowledge, experience, and information from the scientific community, organizations, government agencies and individuals.
Foodconsumer.org encourages readers who have had medical conditions to consult with licensed health care providers - conventional and or alternative medical practitioners.