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General Health
Drinking cola bad for bone health
By Sue Mueller
Apr 26, 2008 - 2:53:47 PM

SATURDAY April 26, 2008 (Foodconsumer.org) -- Drinking cola may not be good for bone health, according to a study published recently in the American Journal of Clinical Nutrition.

The study led by Tucker KL from Tufts University and colleagues showed drinking cola is associated with lower bone mass in women.

It is unknown how cola affect bone health, but caffeine is one possible culprit which has been found associated with higher risk of osteoporosis.  Phosphoric acid may be responsible for bone mineral loss.

The Framingham Osteoporosis Study of more than 2,500 men and women at 60 on average found women who drank cola had lower bone mineral density at three hip sites.  The association held true regardless of age, menopause, total calcium and vitamin D intake.

“The mean BMD of those with daily cola intake was 3.7% lower at the femoral neck and 5.4% lower at Ward's area than of those who consumed <1 serving cola/mo,” the researchers write.

Similar associations were found for diet cola and, although weaker, for decaffeinated cola.   But the researchers did not find such an association in men.

No significant association between non-cola carbonated beverage consumption and bone mineral density was observed.  The results suggested that phosphoric acid in colas may be responsible for lowering bone mineral density.

A study led by researchers from Turkey suggested the decrease in bone mineral density might be related to the renal damage caused by cola drinks in addition to other related factors.  The study was published in 2007 in Basic & clinical pharmacology & toxicology.

An earlier study by researchers from Mexico also suggested that heavy intake of cola has the potential of reducing femoral mineral density. The study was published in 2000 in Archives of medical research.


Am J Clin Nutr. 2006 Oct; 84(4):936-42.
Colas, but not other carbonated beverages, are associated with low bone mineral density in older women: The Framingham Osteoporosis Study.
Tucker KL, Morita K, Qiao N, Hannan MT, Cupples LA, Kiel DP.
Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA. katherine.tucker@tufts.edu

Basic Clin Pharmacol Toxicol. 2007 May;100(5):334-8.
Evaluation of the effect of cola drinks on bone mineral density and associated factors.
Ogur R, Uysal B, Ogur T, Yaman H, Oztas E, Ozdemir A, Hasde M.
Department of Environmental Health, Gulhane Medical Faculty, Ankara, Turkey. rogur@gata.edu.tr

Arch Med Res. 2000 Jul-Aug;31(4):360-5.
Cola beverage consumption induces bone mineralization reduction in ovariectomized rats.
García-Contreras F, Paniagua R, Avila-Díaz M, Cabrera-Muñoz L, Martínez-Muñiz I, Foyo-Niembro E, Amato D.
Unidad de Investigación Médica en Enfermedades Nefrológicas, Hospital de Especialidades, México, D.F., Mexico. dantea@cim.spin.com.mx






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