February 09, 2009 - For Immediate Release
WOMEN WHO DRINK TWO-PLUS CANS OF SODA POP PER DAY AT NEARLY TWICE THE RISK FOR EARLY KIDNEY DISEASE
MAYWOOD, Ill. -- Women who drink two or more cans of soda pop per day
are nearly twice as likely to show early signs of kidney disease, a
recent study has found.
researchers did not find an elevated risk for men, or for people who
drink diet soda, said lead researcher David Shoham of Loyola University
The study was published in PLoSONE, a
peer-reviewed journal of science and medical research published by the
Public Library of Science.
Researchers examined data from
a representative sample of 9,358 U.S. adults in the National Health and
Nutrition Examination Survey. The NHANES survey included urine samples
and a questionnaire about dietary habits.
reported drinking two or more sodas in the previous 24 hours were 1.86
times more likely to have albuminuria, a sensitive marker for early
kidney damage. Albuminuria is an excess amount of a protein called
albumin in the urine. Since healthy kidneys filter out large molecules
such as albumin, an excess amount can be a sign of damage to the
About 11 percent of the population has
albuminuria. Among those who drink two or more cans of soda per day, 17
percent have this early marker of kidney disease, the study found. It's
unclear why drinking soda increased the risk only in women, Shoham
said. There may be an unknown underlying cause that is linked to both
soda consumption and kidney damage, he said. Shoham is an assistant
professor in the Department of Preventive Medicine and Epidemiology.
recent years, diabetes, obesity and kidney disease have been
increasing, along with consumption of high fructose corn syrup, the
sweetener used in most sodas.
But what's most important is
the amount of sugar, not the type, Shoham said. "I don?t think there is
anything demonic about high fructose corn syrup per se," Shoham said.
"People are consuming too much sugar. The problem with high fructose
corn syrup is that it contributes to over consumption. It's cheap, it
has a long shelf life and it allows you to buy a case of soda for less
Shoham and colleagues concluded that additional
studies are needed to determine whether the elevated risk of kidney
disease is due to high fructose corn syrup itself, an overall excess
intake of sugar, unmeasured lifestyle factors or other causes.
recent pilot study by other researchers, reported in the journal
Environmental Health, found that nine of 20 commercial samples of high
fructose corn syrup from three manufacturers contained detectable
levels of mercury. "This adds the intriguing possibility that it is not
just the sugar itself in high fructose corn syrup that is harmful,
because mercury is harmful to kidneys as well," Shoham said.
26 million American adults have chronic kidney disease, according to
the National Kidney Foundation. Advanced kidney disease causes such
symptoms as fatigue, poor appetite, trouble sleeping and concentrating
and swollen feet. Kidney disease can lead to high blood pressure,
anemia, nerve damage, weak bones and cardiovascular disease.
study was published in the Oct. 17 edition of PLoSONE. Shoham's
co-authors are Ramon Durazo-Arizu, Holly Kramer, Amy Luke and Richard
Cooper of Loyola University Health System, Suma Vupputuri of Kaiser
Permanente and Abhijit Kshirsagar of the University of North Carolina.
Based in the western suburbs of Chicago, Loyola University Health
System is a quaternary care system with a 61-acre main medical center
campus, the 36-acre Gottlieb hospital campus and 22 primary and
specialty care facilities in Cook, Will and DuPage counties. The
medical center campus is conveniently located in Maywood, 13 miles west
of the Chicago Loop and 8 miles east of Oak Brook, Ill. The heart of
the medical center campus, Loyola University Hospital, is a 570
licensed bed facility. It houses a Level 1 Trauma Center, a Burn Center
and the Ronald McDonald® Children's Hospital of Loyola University
Medical Center. Also on campus are the Cardinal Bernardin Cancer
Center, Loyola Outpatient Center, Center for Heart & Vascular
Medicine and Loyola Oral Health Center as well as the LUC Stritch
School of Medicine, the LUC Marcella Niehoff School of Nursing and the
Loyola Center for Health & Fitness. Loyola's Gottlieb campus in
Melrose Park includes the 250-bed community hospital, the Gottlieb
Health & Fitness Center and the Marjorie G. Weinberg Cancer Care